TRANSLATIONAL MEDICINE AND USE OF BIOMARKERS
PLUBLICATIONS
- Monitoring circulating dipeptidyl peptidase 3 (DPP3) predicts improvement of organ failure and survival in sepsis: a prospective observational multinational study
Alice Blet, Benjamin Deniau, Karine Santos, Dirk P. T. van Lier, Feriel Azibani, Xavier Wittebole, Benjamin G. Chousterman, Etienne Gayat, Oliver Hartmann, Joachim Struck, Andreas Bergmann, Massimo Antonelli, Albertus Beishuizen, Jean-Michel Constantin, Charles Damoisel, Nicolas Deye, Salvatore Di Somma, Thierry Dugernier, Bruno François, Stephane Gaudry, Vincent Huberlant, Jean-Baptiste Lascarrou, Gernot Marx, Emmanuelle Mercier, Haikel Oueslati, Peter Pickkers, Romain Sonneville, Matthieu Legrand, Pierre-François Laterre, Alexandre Mebazaa, AdrenOSS-1 Study Investigators
Crit Care.2021;25: 61.Published online 2021 Feb 15.
doi:10.1186/s13054-021-03471-2 - Proenkephalin Predicts Organ Failure, Renal Replacement Therapy, and Mortality in Patients With Sepsis
Hanah Kim, Mina Hur, Joachim Struck, Andreas Bergmann, Salvatore Di Somma
Ann Lab Med.2020 Nov; 40(6): 466–473.Published online 2020 Nov 1.
doi:10.3343/alm.2020.40.6.466 - The 2019–2020 Novel Coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2) Pandemic: A Joint American College of Academic International Medicine-World Academic Council of Emergency Medicine Multidisciplinary COVID-19 Working Group Consensus Paper Stanislaw P Stawicki, Rebecca Jeanmonod, Andrew C Miller, Lorenzo Paladino, David F Gaieski, Anna Q Yaffee, Annelies De Wulf, Joydeep Grover, Thomas J. Papadimos, Christina Bloem, Sagar C Galwankar, Vivek Chauhan, Michael S. Firstenberg, Salvatore Di Somma, Donald Jeanmonod, Sona M Garg, Veronica Tucci, Harry L Anderson, Lateef Fatimah, Tamara J Worlton, Siddharth P Dubhashi, Krystal S Glaze, Sagar Sinha, Ijeoma Nnodim Opara, Vikas Yellapu, Dhanashree Kelkar, Ayman El-Menyar, Vimal Krishnan, S Venkataramanaiah, Yan Leyfman, Hassan Ali Saoud Al Thani, Prabath WB Nanayakkara, Sudip Nanda, Eric Cioè-Peña, Indrani Sardesai, Shruti Chandra, Aruna Munasinghe, Vibha Dutta, Silvana Teixeira Dal Ponte, Ricardo Izurieta, Juan A Asensio, Manish Garg
J Glob Infect Dis.2020 Apr-Jun;12(2): 47–93. Published online 2020 May 22.
doi:10.4103/jgid.jgid_86_20
- The Integration of qSOFA with Clinical Variables and Serum Biomarkers Improves the Prognostic Value of qSOFA Alone in Patients with Suspected or Confirmed Sepsis at ED Admission
Filippo Mearelli, Giulia Barbati, Chiara Casarsa, Carlo Giansante, Andrea Breglia, Andrea Spica, Cristina Moras, Gaia Olivieri, Alessandro Agostino Occhipinti, Margherita De Nardo, Francesca Spagnol, Nicola Fiotti, Filippo Giorgio Di Girolamo, Maurizio Ruscio, Luigi Mario Castello, Efrem Colonetti, Rossella Marino, Claudio Ronco, Michela Zanetti, Enrico Lupia, Maria Lorenza Muiesan, Salvatore Di Somma, Gian Carlo Avanzi, Gianni Biolo.
J Clin Med. 2020 Apr;9(4): 1205.Published online 2020 Apr 22.
doi:10.3390/jcm9041205 - Bioactive adrenomedullin, proenkephalin A and clinical outcomes in an acute heart failure setting
John Molvin, Amra Jujic, Silvia Navarin, Olle Melander, Giada Zoccoli, Oliver Hartmann, Andreas Bergmann, Joachim Struck, Erasmus Bachus, Salvatore Di Somma, Martin Magnusson.
Open Heart.2019;6(2): e001048.Published online 2019 Jul 3.
doi:10.1136/openhrt-2019-001048 - Establishing national centre for point-of-care technology for ‘Swasth Bharat, Samridh Bharat’
Vivek Chauhan, Sarman Singh, Sagar Galwankar, Praveen Aggarwal, Sanjeev Bhoi, Salvatore Di Somma, W. Frank Peacock, Lorenzo Paladino J Lab Physicians.2019 Jul-Sep;11(3): 177–179.
doi:10.4103/JLP.JLP_139_19 - Circulating Biologically Active Adrenomedullin Predicts Organ Failure and Mortality in Sepsis
Hanah Kim, Mina Hur, Joachim Struck, Andreas Bergmann, Salvatore Di Somma
Ann Lab Med.2019 Sep;39(5): 454–463.Published online 2019 Apr 26.
doi:10.3343/alm.2019.39.5.454 - Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study
Alexandre Mebazaa, Christopher Geven, Alexa Hollinger, Xavier Wittebole, Benjamin Glen Chousterman, Alice Blet, Etienne Gayat, Oliver Hartmann, Paul Scigalla, Joachim Struck, Andreas Bergmann, Massimo Antonelli, Albertus Beishuizen, Jean-Michel Constantin, Charles Damoisel, Nicolas Deye, Salvatore Di Somma, Thierry Dugernier, Bruno François, Stephane Gaudry, Vincent Huberlant, Jean-Baptiste Lascarrou, Gernot Marx, Emmanuelle Mercier, Haikel Oueslati, Peter Pickkers, Romain Sonneville, Matthieu Legrand, Pierre-François Laterre, AdrenOSS-1 study investigators.
Crit Care.2018; 22: 354.Published online 2018 Dec 21.
doi:10.1186/s13054-018-2243-2 - Proenkephalin A 119-159 (Penkid) Is an Early Biomarker of Septic Acute Kidney Injury: The Kidney in Sepsis and Septic Shock (Kid-SSS) Study
Alexa Hollinger, Xavier Wittebole, Bruno François, Peter Pickkers, Massimo Antonelli, Etienne Gayat, Benjamin Glenn Chousterman, Jean-Baptiste Lascarrou, Thierry Dugernier, Salvatore Di Somma, Joachim Struck, Andreas Bergmann, Albertus Beishuizen, Jean-Michel Constantin, Charles Damoisel, Nicolas Deye, Stéphane Gaudry, Vincent Huberlant, Gernot Marx, Emanuelle Mercier, Haikel Oueslati, Oliver Hartmann, Romain Sonneville, Pierre-François Laterre, Alexandre Mebazaa, Matthieu Legrand.
Kidney Int Rep.2018 Nov;3(6): 1424–1433.Published online 2018 Aug 22.
doi:10.1016/j.ekir.2018.08.006 - Biomarkers in Emergency Medicine
Patrizia Cardelli, Mina Hur, Salvatore Di Somma.
Dis Markers.2018;2018: 4597489.Published online 2018 Mar 20.
doi:10.1155/2018/4597489 - Prohormones in the Early Diagnosis of Cardiac Syncope
Patrick Badertscher, Thomas Nestelberger, Jeanne du Fay de Lavallaz, Martin Than, Beata Morawiec, Damian Kawecki, Òscar Miró, Beatriz López, F. Javier Martin‐Sanchez, José Bustamante, Nicolas Geigy, Michael Christ, Salvatore Di Somma, W. Frank Peacock, Louise Cullen, François Sarasin, Dayana Flores, Michael Tschuck, Jasper Boeddinghaus, Raphael Twerenbold, Karin Wildi, Zaid Sabti, Christian Puelacher, Maria Rubini Giménez, Nikola Kozhuharov, Samyut Shrestha, Ivo Strebel, Katharina Rentsch, Dagmar I. Keller, Imke Poepping, Andreas Buser, Wanda Kloos, Jens Lohrmann, Michael Kuehne, Stefan Osswald, Tobias Reichlin, Christian Mueller
J Am Heart Assoc.2017 Dec;6(12): e006592.Published online 2017 Dec 21.
doi:10.1161/JAHA.117.006592 - Proenkephalin, Neutrophil Gelatinase-Associated Lipocalin, and Estimated Glomerular Filtration Rates in Patients With Sepsis
Hanah Kim, Mina Hur, Seungho Lee, Rossella Marino, Laura Magrini, Patrizia Cardelli, Joachim Struck, Andreas Bergmann, Oliver Hartmann, Salvatore Di Somma, GREAT Network
Ann Lab Med.2017 Sep;37(5): 388–397.Published online 2017 Jun 20.
doi:10.3343/alm.2017.37.5.388 - Echocardiography and lung ultrasonography for the assessment and management of acute heart failure
Susanna Price, Elke Platz, Louise Cullen, Guido Tavazzi, Michael Christ, Martin R. Cowie, Alan S. Maisel, Josep Masip, Oscar Miro, John J. McMurray, W. Frank Peacock, F. Javier Martin-Sanchez, Salvatore Di Somma, Hector Bueno, Uwe Zeymer, Christian Mueller
Nat Rev Cardiol. Author manuscript; available in PMC 2018 Jul 1.
Published in final edited form as: Nat Rev Cardiol. 2017 Jul; 14(7): 427–440. Published online 2017 Apr 27.
doi:10.1038/nrcardio.2017.56 - Multi-marker approach using procalcitonin, presepsin, galectin-3, and soluble suppression of tumorigenicity 2 for the prediction of mortality in sepsis
Hanah Kim, Mina Hur, Hee-Won Moon, Yeo-Min Yun, Salvatore Di Somma, on behalf of GREAT Network.
Ann Intensive Care.2017;7: 27.Published online 2017 Mar 7.
doi:10.1186/s13613-017-0252-y - Comparison Between Soluble ST2 and High-Sensitivity Troponin I in Predicting Short-Term Mortality for Patients Presenting to the Emergency Department With Chest Pain
Rossella Marino, Laura Magrini, Francesca Orsini, Veronica Russo, Patrizia Cardelli, Gerardo Salerno, Mina Hur, Salvatore Di Somma, GREAT NETWORK.
Ann Lab Med. 2017 Mar; 37(2): 137–146. Published online 2016 Dec 20.
doi:10.3343/alm.2017.37.2.137 - Soluble Suppression of Tumorigenicity 2 and Echocardiography in Sepsis
Hyun Suk Yang, Mina Hur, Hanah Kim, Laura Magrini, Rossella Marino, Salvatore Di Somma, GREAT Network
Ann Lab Med.2016 Nov;36(6): 590–594.Published online 2016 Aug 24.
doi:10.3343/alm.2016.36.6.590 - Practical approach on frail older patients attended for acute heart failure
Francisco J. Martín-Sánchez, Michael Christ, Òscar Miró, W. Frank Peacock, John J. McMurray, Héctor Bueno, Alan S. Maisel, Louise Cullen, Martin R. Cowie, Salvatore Di Somma, Elke Platz, Josep Masip, Uwe Zeymer, Christiaan Vrints, Susanna Price, Christian Mueller.
Int J Cardiol. Author manuscript; available in PMC 2017 Dec 15.
Published in final edited form as: Int J Cardiol. 2016 Nov 1; 222: 62–71.Published online 2016 Jul 18.
doi:10.1016/j.ijcard.2016.07.151 - Current real-life use of vasopressors and inotropes in cardiogenic shock – adrenaline use is associated with excess organ injury and mortality
Tuukka Tarvasmäki, Johan Lassus, Marjut Varpula, Alessandro Sionis, Reijo Sund, Lars Køber, Jindrich Spinar, John Parissis, Marek Banaszewski, Jose Silva Cardoso, Valentina Carubelli, Salvatore Di Somma, Alexandre Mebazaa, Veli-Pekka Harjola, for the CardShock study investigators.
Crit Care.2016;20: 208.Published online 2016 Jul 4.
doi:10.1186/s13054-016-1387-1 - European Society of Cardiology – Acute Cardiovascular Care Association position paper on safe discharge of acute heart failure patients from the emergency department
Òscar Miró, Frank W Peacock, John J McMurray, Héctor Bueno, Michael Christ, Alan S Maisel, Louise Cullen, Martin R Cowie, Salvatore Di Somma, Francisco J Martín Sánchez, Elke Platz, Josep Masip, Uwe Zeymer, Christiaan Vrints, Susanna Price, Alexander Mebazaa, Christian Mueller.
Eur Heart J Acute Cardiovasc Care. Author manuscript; available in PMC 2018 Jun 1.
Published in final edited form as: Eur Heart J Acute Cardiovasc Care. 2017 Jun; 6(4): 311–320. Published online 2016 Feb 21. doi:10.1177/2048872616633853 - Soluble ST2 Has a Prognostic Role in Patients With Suspected Sepsis
Mina Hur, Hanah Kim, Hyun Jeong Kim, Hyun Suk Yang, Laura Magrini, Rossella Marino, Patrizia Cardelli, Salvatore Di Somma, GREAT Network.
Ann Lab Med.2015 Nov; 35(6): 570–577.Published online 2015 Sep 1.
doi:10.3343/alm.2015.35.6.570 - Serum Cystatin C for the Diagnosis of Acute Kidney Injury in Patients Admitted in the Emergency Department
Cristina Bongiovanni, Laura Magrini, Gerardo Salerno, Chiara Serena Gori, Patrizia Cardelli, Mina Hur, Marco Buggi, Salvatore Di Somma.
Dis Markers. 2015; 2015: 416059. Published online 2015 Jun 15.
doi: 10.1155/2015/416059 - Evidence of Uncoupling between Renal Dysfunction and Injury in Cardiorenal Syndrome: Insights from the BIONICS Study
Matthieu Legrand, Benedetta De Berardinis, Hanna K. Gaggin, Laura Magrini, Arianna Belcher, Benedetta Zancla, Alexandra Femia, Mandy Simon, Shweta Motiwala, Rasika Sambhare, Salvatore Di Somma, Alexandre Mebazaa, Vishal S. Vaidya, James L. Januzzi, Jr, from the Global Research on Acute Conditions Team (GREAT).
PLoS One. 2014; 9(11): e112313. Published online 2014 Nov 11.
doi: 10.1371/journal.pone.0112313 - Neutrophil Gelatinase-Associated Lipocalin: Ready for Routine Clinical Use? An International Perspective
Claudio Ronco, Matthieu Legrand, Stuart L. Goldstein, Mina Hur, Nam Tran, Eric C. Howell, Vincenzo Cantaluppi, Dinna N. Cruz, Kevin Damman, Sean M. Bagshaw, Salvatore Di Somma, Andrew Lewington.
Blood Purif. Author manuscript; available in PMC 2016 Apr 23.
Published in final edited form as: Blood Purif. 2014; 37(4): 271–285.Published online 2014 Jul 3.
doi: 10.1159/000360689 - Usefulness of Combining Galectin-3 and BIVA Assessments in Predicting Short- and Long-Term Events in Patients Admitted for Acute Heart Failure
Benedetta De Berardinis, Laura Magrini, Giorgio Zampini, Benedetta Zancla, Gerardo Salerno, Patrizia Cardelli, Enrico Di Stasio, Hanna K. Gaggin, Arianna Belcher, Blair A. Parry, John T. Nagurney, James L. Januzzi, Jr., Salvatore Di Somma.
Biomed Res Int. 2014; 2014: 983098. Published online 2014 Jun 30.
doi: 10.1155/2014/983098 - Diagnostic and prognostic utilities of multimarkers approach using procalcitonin, B-type natriuretic peptide, and neutrophil gelatinase-associated lipocalin in critically ill patients with suspected sepsis
Mina Hur, Hanah Kim, Seungho Lee, Flavia Cristofano, Laura Magrini, Rossella Marino, Chiara Serena Gori, Cristina Bongiovanni, Benedetta Zancla, Patrizia Cardelli, Salvatore Di Somma.
BMC Infect Dis.2014;14: 224.Published online 2014 Apr 24.
doi:10.1186/1471-2334-14-224 - Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial
Maggioni AP, Greene SJ, Fonarow GC, et al. Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial.
Eur Heart J. 2013;34(40):3117-3127.
doi:10.1093/eurheartj/eht342 - Implementation of Novel Biomarkers in the Diagnosis, Prognosis, and Management of Acute Kidney Injury: Executive Summary from the Tenth Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)
Peter A. McCullough, Josee Bouchard, Sushrut S. Waikar, Edward D. Siew, Zoltan H. Endre, Stuart L. Goldstein, Jay L. Koyner, Etienne Macedo, Kent Doi, Salvatore Di Somma, Andrew Lewington, Ravi Thadhani, Raj Chakravarthi, Can Ice, Mark D. Okusa, Jacques Duranteau, Peter Doran, Li Yang, Bertrand L. Jaber, Shane Meehan, John A. Kellum, Michael Haase, Patrick T. Murray, Dinna Cruz, Alan Maisel, Sean M. Bagshaw, Lakhmir S. Chawla, Ravindra L. Mehta, Andrew D. Shaw, Claudio Ronco.
Contrib Nephrol. Author manuscript; available in PMC 2013 Dec 8.
Published in final edited form as: Contrib Nephrol. 2013; 182: 10.1159/000349962.Published online 2013 May 13. doi:10.1159/000349962 - Additive value of blood neutrophil gelatinase-associated lipocalin to clinical judgement in acute kidney injury diagnosis and mortality prediction in patients hospitalized from the emergency department
Salvatore Di Somma, Laura Magrini, Benedetta De Berardinis, Rossella Marino, Enrico Ferri, Paolo Moscatelli, Paola Ballarino, Giuseppe Carpinteri, Paola Noto, Biancamaria Gliozzo, Lorenzo Paladino, Enrico Di Stasio.
Crit Care. 2013; 17(1): R29. Published online 2013 Feb 12.
doi: 10.1186/cc12510 - Utility of Procalcitonin (PCT) and Mid regional pro-Adrenomedullin (MR-proADM) in risk stratification of critically ill febrile patients in Emergency Department (ED). A comparison with APACHE II score
Francesco Travaglino, Benedetta De Berardinis, Laura Magrini, Cristina Bongiovanni, Marcello Candelli, Nicolò Gentiloni Silveri, Jacopo Legramante, Alberto Galante, Gerardo Salerno, Patrizia Cardelli, Salvatore Di Somma.
BMC Infect Dis. 2012; 12: 184. Published online 2012 Aug 8.
doi: 10.1186/1471-2334-12-184 - Use of procalcitonin for the diagnosis of pneumonia in patients presenting with a chief complaint of dyspnoea: results from the BACH (Biomarkers in Acute Heart Failure) trial
Alan Maisel, Sean-Xavier Neath, Judd Landsberg, Christian Mueller, Richard M. Nowak, W. Frank Peacock, Piotr Ponikowski, Martin Möckel, Christopher Hogan, Alan H.B. Wu, Mark Richards, Paul Clopton, Gerasimos S. Filippatos, Salvatore Di Somma, Inder Anand, Leong L. Ng, Lori B. Daniels, Robert H. Christenson, Mihael Potocki, James McCord, Garret Terracciano, Oliver Hartmann, Andreas Bergmann, Nils G. Morgenthaler, Stefan D. Anker.
Eur J Heart Fail.2012 Mar; 14(3): 278–286. Published online 2012 Feb 2.
doi: 10.1093/eurjhf/hfr177 - In-hospital percentage BNP reduction is highly predictive for adverse events in patients admitted for acute heart failure: the Italian RED Study Salvatore Di Somma, Laura Magrini, Valerio Pittoni, Rossella Marino, Antonella Mastrantuono, Enrico Ferri, Paola Ballarino, Andrea Semplicini, Giuliano Bertazzoni, Giuseppe Carpinteri, Paolo Mulè, Maria Pazzaglia, Kevin Shah, Alan Maisel, Paul Clopton.
Crit Care.2010;14(3): R116.Published online 2010 Jun 16.
doi:10.1186/cc9067
